TUF's Research Scholars

The Urology Foundation is delighted to announce that we funded SIX research projects in 2017.

The researchers are working on a wide variety of topics, including PUV, incontinence, and bladder, kidney and prostate cancer.

 

Research Scholars 2017

  • David Thurtle, University of Cambridge

The development and implementation of an individualised prognostic modeling tool for non-metastatic prostate cancer: PREDICT Prostate

Using long-term survival data we will construct, validate and test an individualised prognostic model for non-metastatic prostate cancer, which will be built in to a free-to-use web-based tool to guide and inform patient and clinician decision-making, and improve prostate cancer management.

AT BAUS 2017 Mr Thurtle will receive the TUF Medal for best research application

 

  • Kevin Cao, School of Physiology, Pharmacology & Neuroscience, University of Bristol

The molecular basis of bladder dysfunction in posterior urethral valves

The project will characterise the cellular pathways that cause excessive connective tissue deposition in the bladders of foetal and newborn boys, which leads to severe and life-long problems in their lower urinary tract and even renal function.

 

  • Emma Mironska, Department of Material Sciences and Engineering, University of Sheffield

Use of patient's own fat derived cells for developing materials for pelvic floor regeneration

We propose to use cells derived from the patient’s abdominal fat combined with a biodegradable membrane in theatre to provide a safe and effective alternative to the use of polypropylene in the repair of pelvic organ prolapse.

 

  • Pramit Khetrapal, Division of Surgery & Interventional Science, University College London

Development of cell-free DNA based biomarkers to detect metastatic bladder cancer

To develop and validate a blood-based genomic biomarker to detect micro-metastatic bladder cancer after radical cystectomy, that can be used in the post-operative setting to detect residual disease, and as an adjunct surveillance tool to detect metastatic disease alongside and perhaps before conventional CT imaging.

 

  • Sabrina Rossi, University of Cambridge/Addenbrooke's Hospital

Developing the evidence for risk stratified screening for renal cell carcinoma using focused renal ultrasound: a systematic review of risk prediction models and feasibility study investigating the potential for technician performed ultrasound.

The fellowship aims to develop the evidence for risk-stratified screening for renal cancer: a systematic review of risk prediction models will be performed alongside a feasibility study to assess the ability of technicians with previous experience in performing abdominal aortic aneurysm screening to learn to perform focused renal ultrasound.

 

  • Yiannis Philippou, Nuffield Department of Surgical Sciences, University of Oxford

Combining vascular-targeted photodynamic therapy with radiotherapy for the treatment of locally-advanced and oligometastatic prostate cancer.

To investigate a hitherto untested sequential combination of radiotherapy and a novel minimally invasive ablative therapy termed "vasuclar-targeted photodynamic therapy" in the treatment of locally advanced prostate cancer in pre-clinical models of this malignancy.

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